Exchange Transfusion Blood Group Chart Transfusion with ABO incompatible red cells can lead to severe and potentially fatal transfusion reactions The ABO blood group system contains four different ABO blood groups see Table 1 and is determined by inherited antigens expressed on red cells e g A or B antigens
Calculate volume of blood to be exchanged double volume exchange removes 90 of baby s red cells and 50 of available intravascular bilirubin Use For anaemia without antibodies or hyperbilirubinaemia use single volume exchange For term Exchange transfusion must take place in an Intensive care setting with intensive and physiological biochemical monitoring carried out by staff that are trained in the procedure ideally following written informed parental consent
Exchange Transfusion Blood Group Chart
Exchange Transfusion Blood Group Chart
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What is an exchange transfusion The procedure involves removing your baby s blood in stages and replacing it with fresh donor blood Why is an exchange transfusion needed Your baby may require an exchange transfusion for a number of reasons 1 2 Exchange transfusion may be indicated in significant hyperbilirubinaemia secondary to acute haemolysis by removing the affected red blood cells and circulating maternal antibodies to reduce red cell destruction
Use normal saline for an exchange to lower Hct An exchange is done to raise the HCT when the infant has a chronic anemia with a normal blood volume Use PRBC s to raise Hct An infant s blood volume is 85 ml kg The desired Hct is usually 45 55 Use the following formulas to calculate the amount of the exchange III Pre transfusion compatibility testing History and clinical details checked Blood group ABO and RhD Antibody screen no antibodies detected Issue blood
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Exchange transfusion This LOP is developed to guide clinical practice at the Royal Hospital for Women Individual patient circumstances may mean that practice diverges from this LOP Exchange transfusion is to be performed withhold enteral feeds Recheck bilirubin at start of phototherapy as baseline Consider the use of 360o phototherapy once IV lines sited Consider Intravenous Immunoglobulin IVIG if any anticipated delay in obtaining blood for exchange transfusion see later section in guideline
Exchange transfusion of the neonate is a potentially life saving intervention that involves removing aliquots of blood and replacing with donor blood in order to remove abnormal blood components and circulating toxins whilst maintaining adequate circulating blood volume Exchange transfusion is primarily performed in the setting of severe hyperbilirubinemia due to isoimmune hemolytic disease in order to remove antibodies and excess bilirubin but other indications exist and are discussed below
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Transfusion with ABO incompatible red cells can lead to severe and potentially fatal transfusion reactions The ABO blood group system contains four different ABO blood groups see Table 1 and is determined by inherited antigens expressed on red cells e g A or B antigens
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Calculate volume of blood to be exchanged double volume exchange removes 90 of baby s red cells and 50 of available intravascular bilirubin Use For anaemia without antibodies or hyperbilirubinaemia use single volume exchange For term
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Exchange Transfusion Blood Group Chart - 1 2 Exchange transfusion may be indicated in significant hyperbilirubinaemia secondary to acute haemolysis by removing the affected red blood cells and circulating maternal antibodies to reduce red cell destruction
