Blood Group Chart Antigen Antibody Blood type is determined by which antigens present on red blood cells Antigens are macromolecules usually proteins that can elicit an immune response and help the body determine self vs foreign Antibodies recognize antigens and target them for degradation
There are 4 main blood groups defined by the ABO system blood group A has A antigens on the red blood cells with anti B antibodies in the plasma blood group B has B antigens with anti A antibodies in the plasma blood group O has no antigens but both anti A and anti B antibodies in the plasma blood group AB has both A and B The purpose of this section is to introduce you to Module 3 Blood Group Serology which focuses on blood grouping and compatibility testing LEARNING OBJECTIVES
Blood Group Chart Antigen Antibody
Blood Group Chart Antigen Antibody
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Blood Antigen Chart
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V Antigen Blood Group
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Antibodies anti D may occur after an individual is exposed to D antigens via transfusion pregnancy or organ transplantation These antibodies are clinically significant and can cause haemolytic transfusion reactions and result in haemolytic disease ABO blood group antigens present on red blood cells and IgM antibodies present in the serum The ABO blood group system is used to denote the presence of one both or neither of the A and B antigens on erythrocytes red blood cells 1
Anti A and anti B bind to RBCs and activate the complement cascade which lyses the RBCs while they are still in the circulation intravascular hemolysis Most deaths caused by blood transfusion are the result of transfusing ABO incompatible blood The ABO system is the only blood group system in which individuals generate antibodies to antigens absent from their erythrocytes without prior exposure to those antigens Other blood group systems require exposure such as
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Blood Antigen Chart
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Blood Antigen Chart
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Blood Antigen Chart
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There are therefore 4 main ABO groups A B AB and O Antibodies agglutinins for the antigens A and B exist in the plasma and these are termed anti A and anti B The corresponding antigen and antibody are never found in the same individual since when mixed they form antigen antibody complexes effectively agglutinating the blood 1 An introduction to blood groups 1 What is a blood group 1 Blood group antibodies 3 Clinical importance of blood groups 3 Biological importance of blood groups 3 Blood group systems 4 Blood group terminology and classification 4 2 Techniques used in blood grouping 8 Factors affecting antigen antibody reactions 8 Temperature 8
There are four major blood groups determined by the presence or absence of two antigens A and B on the surface of red blood cells In addition to the A and B antigens there is a protein called the Rh factor which can be either present or absent creating the 8 most common blood types A A B B O O AB AB The ABO blood group antigens are attached to oligosaccharide chains that project above the RBC surface These chains are attached to proteins and lipids that lie in the RBC membrane Molecular basis The ABO gene indirectly encodes the ABO blood group antigens The ABO locus has three main allelic forms A B and O The A and B alleles each
Blood Antigen Chart
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Blood Antigen Chart
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Blood type is determined by which antigens present on red blood cells Antigens are macromolecules usually proteins that can elicit an immune response and help the body determine self vs foreign Antibodies recognize antigens and target them for degradation
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There are 4 main blood groups defined by the ABO system blood group A has A antigens on the red blood cells with anti B antibodies in the plasma blood group B has B antigens with anti A antibodies in the plasma blood group O has no antigens but both anti A and anti B antibodies in the plasma blood group AB has both A and B
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Blood Group Chart Antigen Antibody - There are many different Rh antigens but only 5 are clinically significant D C c E and e Rh D is the most immunogenic i e likely to produce an immune response and therefore the most likely to precipitate a transfusion reaction
